Fig. 1 · Structure

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β-Aminopropionitrile

Lysyl Oxidase Inhibitor

β-Aminopropionitrile (BAPN) is an irreversible and orally active inhibitor of lysyl oxidase (LOX) and its isoenzymes. By targeting the active site of these enzymes, BAPN effectively disrupts collagen and elastin cross-linking, which is crucial for extracellular matrix stability. This compound is primarily used in research applications focusing on fibrosis, cardiovascular diseases, and various connective tissue disorders, providing valuable insights into the roles of LOX in pathophysiology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 151-18-8
Applications Lysyl Oxidase Inhibitor
Formula C3H6N2
Molecular Weight 70.09
Synonyms BAPN
SMILES
N#CCCN

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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