β-D-glucuronide-pNP-carbonate

Catalog No.: A42565
ADC Linker
β-D-glucuronide-pNP-carbonate is a cleavable linker specifically designed for use in antibody-drug conjugates (ADCs). It facilitates the release of cytotoxic drugs in targeted therapeutic applications, thereby enhancing the efficacy of treatment while minimizing off-target effects. This compound is valuable for researchers focusing on the development of ADCs aimed at improving precision in cancer therapies and other diseases.
Grouped product items
Size Price Stock Qty
5mg
$30.00
In stock
10mg
$45.00
In stock
25mg
$75.00
In stock
50mg
$105.00
In stock
100mg
$180.00
In stock
250mg
$390.00
In stock
1g
$1,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionβ-D-glucuronide-pNP-carbonate is a cleavable linker specifically designed for use in antibody-drug conjugates (ADCs). It facilitates the release of cytotoxic drugs in targeted therapeutic applications, thereby enhancing the efficacy of treatment while minimizing off-target effects. This compound is valuable for researchers focusing on the development of ADCs aimed at improving precision in cancer therapies and other diseases.
Product Information
Catalog NumA42565
FormulaC45H43N3O18
Molecular Weight913.83
CAS Number894095-98-8
SMILESO=C(NCCC(NC(C=C1COC(OC(C=C2)=CC=C2[N+]([O-])=O)=O)=C(C=C1)O[C@H](O[C@@H]3C(OC)=O)[C@@H]([C@H]([C@@H]3OC(C)=O)OC(C)=O)OC(C)=O)=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2