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β-Glucuronide-dPBD-PEG6-NH2

Linker-Payload of ADC

β-Glucuronide-dPBD-PEG6-NH2 serves as a linker-payload in antibody-drug conjugates (ADCs), facilitating targeted delivery of cytotoxic agents to cancer cells. This compound is designed to enhance the stability and efficacy of ADCs through its structural properties, improving therapeutic outcomes in cancer treatment. Its application in bioconjugation allows for the selective release of the drug upon internalization by the target cells, making it a valuable reagent for researchers focusing on advanced drug delivery systems.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2486273-41-8
Applications	Linker-Payload of ADC
Formula	C₈₀H₁₀₅N₇O₃₅
Molecular Weight	1724.72
SMILES	NCCOCCOCCOCCOCCOCCOCCNC(C(C=C1COC(N2C3=CC(OCCCCCOC4=C(C=C5C(N6CC(C[C@@](C(O)N(C5=C4)C(OCC7=CC(C(NCCOC)=O)=C(O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)C(O)=O)O)O)O)C=C7)=O)6[H])=C)=O)OC)=C(OC)C=C3C(N9[C@](CC(C9)=C)([H])C2O)=O)=O)=C(C=C1)O[C@@H]%10O[C@@H]([C@H]([C@@H]([C@H]%10O)O)O)C(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.