Fig. 1 · Structure
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β-Lactamase-IN-7
Cat. No.
A49747
CAS
2419903-21-0
Metallo-β-lactamase Inhibitor
β-Lactamase-IN-7 is a potent inhibitor of VIM-type metallo-β-lactamases, exhibiting inhibition constants (Ki) of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. This compound demonstrates effective inhibition against Klebsiella pneumoniae, making it valuable for studies focused on antibiotic resistance and the development of novel therapeutic strategies against resistant bacterial infections. Its role in characterizing metallo-β-lactamase activity positions it as an important tool in chemical biology research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2419903-21-0 |
| Applications | Metallo-β-lactamase Inhibitor |
| Formula | C16H15N3S2 |
| Molecular Weight | 313.44 |
| SMILES | S=C1NN=C(C2=CC=CC=C2)N1CCSC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.