Balanophonin B is a selective inhibitor of lipopolysaccharide (LPS)-induced nitric oxide (NO) production, exhibiting an IC50 of 1.46 μg/mL. Isolated from Lithocarpus pachylepis, this compound effectively reduces NO production in LPS-stimulated RAW264.7 macrophages, demonstrating significant anti-inflammatory activity. Balanophonin B is valuable for anti-inflammatory drug development and serves as a tool in the biological activity research of natural lignan compounds.
Balanophonin B is a selective inhibitor of lipopolysaccharide (LPS)-induced nitric oxide (NO) production, exhibiting an IC50 of 1.46 μg/mL. Isolated from Lithocarpus pachylepis, this compound effectively reduces NO production in LPS-stimulated RAW264.7 macrophages, demonstrating significant anti-inflammatory activity. Balanophonin B is valuable for anti-inflammatory drug development and serves as a tool in the biological activity research of natural lignan compounds.
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