Fig. 1 · Structure
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BAP1-IN-1
BAP1 Inhibitor
BAP1-IN-1 is a selective inhibitor of BRCA1 associated protein 1 (BAP1), exhibiting an IC50 range of 0.1-1 μM. This compound effectively modulates BAP1 enzymatic activity, making it valuable for studies investigating the role of BAP1 in DNA repair mechanisms and tumorigenesis. Its ability to inhibit BAP1 provides a useful tool for researchers exploring therapeutic strategies in cancers associated with BAP1 dysregulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 353495-21-3 |
| Applications | BAP1 Inhibitor |
| Formula | C18H16N2O2 |
| Molecular Weight | 292.33 |
| SMILES | O=[N+](C1=CC2=C(NC(C3=CC=CC=C3)C4C2C=CC4)C=C1)[O-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.