BAY 41-8543

Catalog No.: A60869
sGC Stimulator
BAY 41-8543 is a soluble guanylyl cyclase (sGC) stimulator that functions independently of nitric oxide (NO). It exhibits vasodilatory effects in both pulmonary and systemic vascular beds in rat models. Additionally, BAY 41-8543 demonstrates antiplatelet activity, making it a valuable tool for research in cardiovascular diseases.
Grouped product items
Size Price Stock Qty
2mg
$25.00
In stock
5mg
$40.00
In stock
10mg
$65.00
In stock
25mg
$135.00
In stock
50mg
$205.00
In stock
100mg
$295.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBAY 41-8543 is a soluble guanylyl cyclase (sGC) stimulator that functions independently of nitric oxide (NO). It exhibits vasodilatory effects in both pulmonary and systemic vascular beds in rat models. Additionally, BAY 41-8543 demonstrates antiplatelet activity, making it a valuable tool for research in cardiovascular diseases.
Product Information
Catalog NumA60869
FormulaC21H21FN8O
Molecular Weight420.44
CAS Number256498-66-5
SMILESNC1=NC(C2=NN(CC3=CC=CC=C3F)C4=NC=CC=C42)=NC(N)=C1N5CCOCC5
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