Fig. 1 · Structure
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BAY 41-8543
sGC Stimulator
BAY 41-8543 is a soluble guanylyl cyclase (sGC) stimulator that functions independently of nitric oxide (NO). It exhibits vasodilatory effects in both pulmonary and systemic vascular beds in rat models. Additionally, BAY 41-8543 demonstrates antiplatelet activity, making it a valuable tool for research in cardiovascular diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 256498-66-5 |
| Applications | sGC Stimulator |
| Formula | C21H21FN8O |
| Molecular Weight | 420.44 |
| SMILES | NC1=NC(C2=NN(CC3=CC=CC=C3F)C4=NC=CC=C42)=NC(N)=C1N5CCOCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.