Fig. 1 · Structure

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BAY-593 hydrochloride

GGTase-I Inhibitor

BAY-593 hydrochloride is a potent GGTase-I inhibitor, effectively disrupting YAP1/TAZ signaling pathways. This compound demonstrates significant antitumor activity in preclinical models, making it a valuable tool for cancer research. Its oral bioavailability enhances its application in vivo, facilitating studies on the mechanistic role of GGTase-I in tumor biology and potential therapeutic strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2413020-57-0
Applications GGTase-I Inhibitor
Formula C26H32ClF3N2O3
Molecular Weight 512.99
SMILES
O=C(N1CCC2(CCNC[C@@]2([H])C3=CC=CC=C3OC)CC1)[C@@](OC)(C(F)(F)F)C4=CC=CC=C4.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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