Fig. 1 · Structure
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BAY-593
GGTase-I Inhibitor
BAY-593 is an orally active inhibitor of geranylgeranyltransferase I (GGTase-I), targeting the post-translational modification critical for protein function. This compound effectively disrupts YAP1/TAZ signaling pathways, which are often associated with cancer progression. BAY-593 has demonstrated potential antitumor activity, making it a valuable tool for research into cancer biology and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2413020-56-9 |
| Applications | GGTase-I Inhibitor |
| Formula | C26H31F3N2O3 |
| Molecular Weight | 476.53 |
| SMILES | O=C(N1CCC2(CCNC[C@@]2([H])C3=CC=CC=C3OC)CC1)[C@@](OC)(C(F)(F)F)C4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.