Fig. 1 · Structure
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BAY 60-2770
sGC Activator
BAY 60-2770 is a selective and orally active soluble guanylyl cyclase (sGC) activator that enhances sGC activity independent of nitric oxide. This compound exhibits significant antifibrotic properties, making it a valuable tool for research into fibrosis and related diseases. Its unique mechanism of action allows for exploration in various biological pathways associated with cardiovascular and respiratory health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1027642-43-8 |
| Applications | sGC Activator |
| Formula | C35H33F4NO5 |
| Molecular Weight | 623.63 |
| SMILES | O=C(O)C1=CC=C(CN(CCCCC(O)=O)CCC2=CC(F)=CC=C2OCC3=CC=C(C4=CC=C(C(F)(F)F)C=C4)C=C3)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.