Fig. 1 · Structure
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BAY-707 acetate
MTH1 Inhibitor
BAY-707 acetate is a potent and selective substrate-competitive inhibitor of MTH1, effectively disrupting DNA and RNA synthesis. With its superior cellular target engagement and favorable pharmacokinetic properties, this compound is ideal for studies investigating nucleotide metabolism and its implications in cancer research. BAY-707 acetate can be utilized to explore the physiological roles of MTH1 and to develop therapeutic strategies against MTH1-dependent tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2223023-19-4 |
| Applications | MTH1 Inhibitor |
| Formula | C17H24N4O4 |
| Molecular Weight | 348.40 |
| SMILES | CC(O)=O.CCNC(C1=CC2=C(N3[C@H](COCC3)C)C=CN=C2N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.