Bazedoxifene-d4 is a deuterium-labeled analog of Bazedoxifene, a nonsteroidal selective estrogen receptor modulator (SERM) that exhibits a potent affinity for estrogen receptors ERα and ERβ, with IC50 values of 23 nM and 99 nM, respectively. This compound is utilized in research focused on osteoporosis and has been shown to inhibit IL-6/GP130 protein-protein interactions, making it relevant for studies related to pancreatic cancer. Its stable isotope labeling facilitates advanced metabolic and pharmacokinetic investigations.
Bazedoxifene-d4 is a deuterium-labeled analog of Bazedoxifene, a nonsteroidal selective estrogen receptor modulator (SERM) that exhibits a potent affinity for estrogen receptors ERα and ERβ, with IC50 values of 23 nM and 99 nM, respectively. This compound is utilized in research focused on osteoporosis and has been shown to inhibit IL-6/GP130 protein-protein interactions, making it relevant for studies related to pancreatic cancer. Its stable isotope labeling facilitates advanced metabolic and pharmacokinetic investigations.
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