Fig. 1 · Structure
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BChE-IN-11
BChE Inhibitor
BChE-IN-11 is a potent and selective non-competitive inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 2.1 μM. This compound is primarily utilized in research related to Alzheimer's disease, where it aids in the examination of cholinergic dysfunction. Its capacity to effectively inhibit BChE makes it a valuable tool for studying disease mechanisms and potential therapeutic strategies in neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 133740-30-4 |
| Applications | BChE Inhibitor |
| Formula | C22H18O4 |
| Molecular Weight | 346.38 |
| SMILES | OC1=CC(OC)=C2C3=CC=C(O)C=C3C=CC2=C1CC4=CC=C(O)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.