Fig. 1 · Structure

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BChE-IN-12

BChE Inhibitor

BChE-IN-12 is a non-competitive inhibitor of butyrylcholinesterase (BChE) with an IC50 value of 2.3 μM. Isolated from Bletilla striata, this compound demonstrates significant inhibitory activity that can aid in the investigation of cholinergic dysfunction. BChE-IN-12 is particularly relevant for research applications focused on Alzheimer's disease and other cognitive disorders where BChE modulation may play a therapeutic role.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 136966-86-4
Applications BChE Inhibitor
Formula C31H30O5
Molecular Weight 482.57
SMILES
OC1=CC(OC)=C2C3=CC=C(O)C(CC4=CC=C(O)C=C4)=C3C=CC2=C1CC5=CC=C(O)C=C5.CC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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