Fig. 1 · Structure
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BChE-IN-14
BChE Inhibitor
BChE-IN-14 is a selective butyrylcholinesterase (BChE) inhibitor, demonstrating IC50 values of 0.23 μM for equine BChE and 0.011 μM for human BChE. This compound exhibits favorable blood-brain barrier permeability and primary cell safety, making it suitable for in vivo studies. BChE-IN-14 has potential in restoring cognitive function, positioning it as a valuable tool for research into Alzheimer’s disease and related neurodegenerative conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2700896-78-0 |
| Applications | BChE Inhibitor |
| Formula | C24H29N |
| Molecular Weight | 331.49 |
| SMILES | CCCCN(CC1=CC=C2C=CC=CC2=C1)CCCC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.