BChE-IN-14 is a selective butyrylcholinesterase (BChE) inhibitor, demonstrating IC50 values of 0.23 μM for equine BChE and 0.011 μM for human BChE. This compound exhibits favorable blood-brain barrier permeability and primary cell safety, making it suitable for in vivo studies. BChE-IN-14 has potential in restoring cognitive function, positioning it as a valuable tool for research into Alzheimer’s disease and related neurodegenerative conditions.
BChE-IN-14 is a selective butyrylcholinesterase (BChE) inhibitor, demonstrating IC50 values of 0.23 μM for equine BChE and 0.011 μM for human BChE. This compound exhibits favorable blood-brain barrier permeability and primary cell safety, making it suitable for in vivo studies. BChE-IN-14 has potential in restoring cognitive function, positioning it as a valuable tool for research into Alzheimer’s disease and related neurodegenerative conditions.
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