BChE-IN-20 is a potent and selective inhibitor of butyrylcholinesterase (BChE), demonstrating IC50 values of 105 nM for equine BChE and 2.3 nM for human BChE. Additionally, it inhibits P-glycoprotein with an IC50 of 0.27 μM. This compound serves as a valuable template for the design and development of BChE-selective ligands relevant to pharmacological research, including inhibitors and fluorogenic probes.
BChE-IN-20 is a potent and selective inhibitor of butyrylcholinesterase (BChE), demonstrating IC50 values of 105 nM for equine BChE and 2.3 nM for human BChE. Additionally, it inhibits P-glycoprotein with an IC50 of 0.27 μM. This compound serves as a valuable template for the design and development of BChE-selective ligands relevant to pharmacological research, including inhibitors and fluorogenic probes.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
