Fig. 1 · Structure

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BChE-IN-38

BChE Inhibitor

BChE-IN-38 is a potent butyrylcholinesterase (BChE) inhibitor demonstrating impressive Ki values of 62.05 nM for human carbonic anhydrase I (hCAI), 28.78 nM for human carbonic anhydrase II (hCAII), 14.09 nM for acetylcholinesterase (AChE), and 1.15 nM for BChE. In addition to its inhibitory effects, BChE-IN-38 exhibits notable cytotoxic activity. This compound is essential for research applications focusing on neurodegenerative disorders, drug development targeting cholinergic systems, and the study of enzyme inhibition mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3054159-55-3
Applications BChE Inhibitor
Formula C27H20N4
Molecular Weight 400.47
SMILES
N1(CC2=CN(C3=C4C(C=CC=C4)=CC=C3)N=N2)C5=CC=CC=C5C=CC6=CC=CC=C61

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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