BChE-IN-5

Catalog No.: A78735
BChE Inhibitor
BChE-IN-5 is a selective inhibitor of butyrylcholinesterase (BChE) with an IC50 of 2.8 nM, demonstrating greater potency against human BChE compared to human acetylcholinesterase (hAChE). This compound is valuable for research focused on neurodegenerative disorders, particularly Alzheimer's disease, by modulating cholinergic signaling pathways. Its specificity and efficacy make BChE-IN-5 a significant tool in elucidating the role of BChE in cognitive decline and related pathologies.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBChE-IN-5 is a selective inhibitor of butyrylcholinesterase (BChE) with an IC50 of 2.8 nM, demonstrating greater potency against human BChE compared to human acetylcholinesterase (hAChE). This compound is valuable for research focused on neurodegenerative disorders, particularly Alzheimer's disease, by modulating cholinergic signaling pathways. Its specificity and efficacy make BChE-IN-5 a significant tool in elucidating the role of BChE in cognitive decline and related pathologies.
Product Information
Catalog NumA78735
FormulaC30H42N4O
Molecular Weight474.68
CAS Number2983586-25-8
SMILESO=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2