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BChE-IN-5

BChE Inhibitor

BChE-IN-5 is a selective inhibitor of butyrylcholinesterase (BChE) with an IC50 of 2.8 nM, demonstrating greater potency against human BChE compared to human acetylcholinesterase (hAChE). This compound is valuable for research focused on neurodegenerative disorders, particularly Alzheimer's disease, by modulating cholinergic signaling pathways. Its specificity and efficacy make BChE-IN-5 a significant tool in elucidating the role of BChE in cognitive decline and related pathologies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2983586-25-8
Applications	BChE Inhibitor
Formula	C₃₀H₄₂N₄O
Molecular Weight	474.68
SMILES	O=C(NCCC1CCN(CCC1)CC2=CC=CC=C2)[C@@H](NCCCC)CC3=CNC4=CC=CC=C34

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.