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BCN-sulfonamide-PEG2-sulfonamide-N-bis(ethanol)

Catalog No.: A81334
Ligands for Target Protein for PROTAC
BCN-sulfonamide-PEG2-sulfonamide-N-bis(ethanol) serves as a versatile ligand for target proteins in PROTAC applications. This compound incorporates a sulfonamide linker designed to enhance the solubility of linker-conjugates. It is particularly useful in the synthesis of PROTACs aimed at inducing targeted degradation of proteins with potential antitumor activity.
BCN-sulfonamide-PEG2-sulfonamide-N-bis(ethanol) 2126749-81-1 Ligands for Target Protein for PROTAC
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBCN-sulfonamide-PEG2-sulfonamide-N-bis(ethanol) serves as a versatile ligand for target proteins in PROTAC applications. This compound incorporates a sulfonamide linker designed to enhance the solubility of linker-conjugates. It is particularly useful in the synthesis of PROTACs aimed at inducing targeted degradation of proteins with potential antitumor activity.
Product Information
Catalog NumA81334
FormulaC20H34N4O11S2
Molecular Weight570.63
CAS Number2126749-81-1
SMILESOCCN(CCO)S(NC(OCCOCCNS(NC(OC[C@@H]1[C@@]2([H])[C@]1([H])CCC#CCC2)=O)(=O)=O)=O)(=O)=O
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PROTAC > Ligand for Target Protein for PROTAC
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