BD-105 is a glucagon-binding fluorescent probe with a dissociation constant (Ka) of 13.3 μM. This reagent displays significant changes in fluorescence intensity upon binding to glucagon, enabling the visualization of glucagon-secreting cells in various biological contexts. BD-105 selectively labels these cells while avoiding staining of insulin-secreting and non-endocrine control cells. It is an invaluable tool for imaging glucagon in live cells and tissues, facilitating studies in metabolic regulation and endocrine functions.
BD-105 is a glucagon-binding fluorescent probe with a dissociation constant (Ka) of 13.3 μM. This reagent displays significant changes in fluorescence intensity upon binding to glucagon, enabling the visualization of glucagon-secreting cells in various biological contexts. BD-105 selectively labels these cells while avoiding staining of insulin-secreting and non-endocrine control cells. It is an invaluable tool for imaging glucagon in live cells and tissues, facilitating studies in metabolic regulation and endocrine functions.
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