Fig. 1 · Structure

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Beauverolide Ja

Calmodulin Inhibitor

Beauverolide Ja is a potent calmodulin (CaM) inhibitor, demonstrating a Kd of 0.078 μM and a Ki of 0.39 μM for the Ca2+-CaM complex. This cyclotetradepsipeptide, derived from the secondary metabolite of Isaria fumosorosea, is valuable for research investigating calmodulin's role in calcium signaling pathways. Its effective inhibition of calmodulin can facilitate studies into various biological processes and potential therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 76265-41-3
Applications Calmodulin Inhibitor
Formula C35H46N4O5
Molecular Weight 602.76
SMILES
O=C(N[C@H](C(N[C@](C(OC(CC(N1)=O)C(C)CCCC)=O)([H])[C@@H](C)CC)=O)CC2=CC=CC=C2)[C@@H]1CC3=CNC4=CC=CC=C34

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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