Fig. 1 · Structure
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Beclin1-ATG14L interaction inhibitor 1
Beclin1-ATG14L Inhibitor
Beclin1-ATG14L interaction inhibitor 1 is a selective inhibitor targeting the interaction between Beclin1 and ATG14L. This compound specifically disrupts the formation of VPS34 complex I, thereby inhibiting autophagy, while leaving VPS34 complex II and its associated vesicle transport unaffected. Its ability to selectively inhibit this interaction makes it a valuable tool for research into autophagy and associated cellular processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1243063-73-1 |
| Applications | Beclin1-ATG14L Inhibitor |
| Formula | C23H24N4O5S |
| Molecular Weight | 468.53 |
| SMILES | O=C1N(CC2=NOC(C3CCC3)=N2)C4=CC(S(=O)(NC5=CC=CC(C)=C5C)=O)=CC=C4OC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.