Benoxacor is a herbicide safener that primarily acts as a regulator of xenobiotic metabolism. It protects maize from metolachlor toxicity by inducing detoxifying enzymes, such as Glutathione S-transferase, while also activating nuclear receptors like FXR, PXR, and ERRα, and inhibiting aromatase. Research indicates that Benoxacor may exhibit subacute oral toxicity and has been associated with hepatotoxicity in animal models, leading to effects on organ weights and alterations in gut microbiota. This compound is relevant for studies on hepatic steatosis, infertility, breast cancer, and developmental toxicity.
Benoxacor is a herbicide safener that primarily acts as a regulator of xenobiotic metabolism. It protects maize from metolachlor toxicity by inducing detoxifying enzymes, such as Glutathione S-transferase, while also activating nuclear receptors like FXR, PXR, and ERRα, and inhibiting aromatase. Research indicates that Benoxacor may exhibit subacute oral toxicity and has been associated with hepatotoxicity in animal models, leading to effects on organ weights and alterations in gut microbiota. This compound is relevant for studies on hepatic steatosis, infertility, breast cancer, and developmental toxicity.
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