Benzaldehyde-PEG4-azide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting targeted protein degradation pathways. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds, facilitating diverse chemical coupling applications in chemical biology research.
Benzaldehyde-PEG4-azide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting targeted protein degradation pathways. This compound features an azide functional group, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds, facilitating diverse chemical coupling applications in chemical biology research.
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