Fig. 1 · Structure
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Benzyl 2-oxo-7-azaspiro3.5nonane-7-carboxylate
PROTAC Linker
Benzyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate serves as a PROTAC linker that is crucial for the design and synthesis of targeted protein degradation (TPD) bioconjugates. This compound facilitates the conjugation of E3 ligase recruiting elements to target proteins, thereby enabling the degradation of unwanted proteins within cells. Its structural characteristics make it a valuable tool for researchers exploring the therapeutic potential of PROTAC technology in various diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 147610-98-8 |
| Applications | PROTAC Linker |
| Formula | C16H19NO3 |
| Molecular Weight | 273.33 |
| SMILES | O=C(OCC=1C=CC=CC1)N2CCC3(CC(=O)C3)CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.