Fig. 1 · Structure

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Benzyl-PEG24-MS

PROTAC Linkers

Benzyl-PEG24-MS is a PEG-based linker designed for use in the synthesis of proteolysis targeting chimeras (PROTACs). This compound facilitates the precise conjugation of target protein ligands and ubiquitin E3 ligase binding domains, enhancing the design of bifunctional molecules for targeted protein degradation. Its unique structure allows for increased solubility and improved biocompatibility, making it suitable for various applications in the study of targeted therapies and protein modulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2218463-20-6
Applications PROTAC Linkers
Formula C56H106O27S
Molecular Weight 1243.49
SMILES
CS(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC1=CC=CC=C1)(=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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