Fig. 1 · Structure

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Benzyl-PEG4-MS

PROTAC Linker

Benzyl-PEG4-MS is a polyethylene glycol (PEG) linker designed for use in proteolysis-targeting chimeras (PROTACs). It facilitates the conjugation of protein degraders, enhancing the efficacy of targeted protein degradation by improving solubility and pharmacokinetic properties. This reagent is essential for researchers focusing on the development of novel therapeutic strategies targeting specific proteins for degradation in various biological contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 477781-69-4
Applications PROTAC Linker
Formula C16H26O7S
Molecular Weight 362.44
SMILES
O=S(OCCOCCOCCOCCOCC1=CC=CC=C1)(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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