Fig. 1 · Structure
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Benzyl-PEG4-Ots
PROTAC Linker
Benzyl-PEG4-Ots is a PEG-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). It facilitates the formation of PROTACs by providing a stable link that enhances the molecular interaction between a target protein and an E3 ligase. This compound is pivotal in research applications aimed at targeted protein degradation, enabling studies in cellular biology, therapeutic development, and the manipulation of protein levels in various disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 89346-82-7 |
| Applications | PROTAC Linker |
| Formula | C22H30O7S |
| Molecular Weight | 438.53 |
| SMILES | O=S(C1=CC=C(C)C=C1)(OCCOCCOCCOCCOCC2=CC=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.