Fig. 1 · Structure
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Benzyl-PEG8-THP
PROTAC Linker
Benzyl-PEG8-THP is a PEG-based PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound promotes the targeted degradation of specific proteins through an E3 ubiquitin ligase-mediated pathway. Its application is essential in drug discovery and development for creating novel therapeutics that modulate protein levels in a highly selective manner.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1611489-00-9 |
| Applications | PROTAC Linker |
| Formula | C28H48O10 |
| Molecular Weight | 544.67 |
| SMILES | C1(COCCOCCOCCOCCOCCOCCOCCOCCOC2OCCCC2)=CC=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.