Fig. 1 · Structure
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Bersiporocin
Prolyl-tRNA Synthetase Inhibitor
Bersiporocin is a potent inhibitor of prolyl-tRNA synthetase, exhibiting an IC50 of less than 100 nM for phosphoribosylpyrophosphate synthetase (PRS). This compound demonstrates significant antifibrotic activity, making it a valuable tool for research into the mechanisms of fibrosis and potential therapeutic interventions. Its specific action on prolyl-tRNA synthetase highlights its relevance in studies focused on protein synthesis and cellular function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2241808-52-4 |
| Applications | Prolyl-tRNA Synthetase Inhibitor |
| Formula | C15H19Cl2N3O |
| Molecular Weight | 328.24 |
| Synonyms | DWN12088 |
| SMILES | O[C@@H](CCCN1)[C@H]1CCCN2C3=CC=C(Cl)C(Cl)=C3N=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.