Fig. 1 · Structure
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Bevurogant
Cat. No.
A77557
CAS
1817773-66-2
RORγt Antagonist
Bevurogant is a selective antagonist of the retinoid-related orphan receptor gamma t (RORγt), which plays a critical role in immune response and inflammation. This compound is primarily utilized in research focused on chronic inflammatory diseases, offering insights into therapeutic strategies for conditions such as autoimmune disorders. Its ability to modulate RORγt activity makes it a valuable tool in the study of immune regulation and potential treatment pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1817773-66-2 |
| Applications | RORγt Antagonist |
| Formula | C26H28N8O3S |
| Molecular Weight | 532.62 |
| Synonyms | BI 730357 |
| SMILES | C[C@@H](C1CC1)N2C3=NC(C4=C(C)N=CN=C4C5CC5)=NC=C3N=C(C2=O)NCC6=CC=C(C=N6)S(C)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.