Fig. 1 · Structure
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BGC-20-1531 hydrochloride
EP4 Receptor Antagonist
BGC-20-1531 hydrochloride is a potent and selective antagonist of the prostanoid EP4 receptor, exhibiting a pKb of 7.6. This compound is primarily utilized in research related to migraine headaches, where modulation of the EP4 receptor may influence pain pathways and inflammatory processes. Its specificity makes it a valuable tool for investigating the roles of prostanoid signaling in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1962928-26-2 |
| Applications | EP4 Receptor Antagonist |
| Formula | C26H25ClN2O6S |
| Molecular Weight | 529.00 |
| Synonyms | PGN 1531 hydrochloride |
| SMILES | CC1=C(COC2=CC=C(C3=NC=C(C=C3)OC)C=C2)C=C(C(NS(C4=CC=CC=C4C)(=O)=O)=O)O1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.