BI-0115 is a selective LOX-1 inhibitor with an IC50 of 5.4 μM, effectively blocking the cellular uptake of oxidized low-density lipoprotein (oxLDL). This compound disrupts receptor activity through the formation of dimers within the homodimeric ligand binding domain. BI-0115 is valuable for research focused on atherosclerosis and cardiovascular diseases, providing insight into the modulation of lipid metabolism and inflammatory processes.
BI-0115 is a selective LOX-1 inhibitor with an IC50 of 5.4 μM, effectively blocking the cellular uptake of oxidized low-density lipoprotein (oxLDL). This compound disrupts receptor activity through the formation of dimers within the homodimeric ligand binding domain. BI-0115 is valuable for research focused on atherosclerosis and cardiovascular diseases, providing insight into the modulation of lipid metabolism and inflammatory processes.
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