Fig. 1 · Structure
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BI-113823
Bradykinin B1 Receptor Antagonist
BI-113823 is a selective antagonist of the bradykinin B1 receptor, exhibiting oral bioactivity. It effectively alleviates mechanical hyperalgesia induced by complete Freund's adjuvant in animal models. This compound is relevant for research focused on chronic inflammatory pain mechanisms and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1119282-90-4 |
| Applications | Bradykinin B1 Receptor Antagonist |
| Formula | C26H44N4O5S |
| Molecular Weight | 524.72 |
| SMILES | O=S(N(C)CCOCC(N([C@@H]1C[C@H](N2CCN(CC2)C)CCC1)C)=O)(C3=C(C=C(C=C3C)OC)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.