Catalog No.: A19071

PHGDH inhibitor


BI-4916 Chemical Structure

CAS NO. 2244451-48-5

BI-4916 is a prodrug of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor.

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Biological Activity

BI-4916 is a prodrug of BI-4924. BI-4924 is a NADH/NAD+-competitive PHGDH inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.96 mL 94.8 mL 189.6 mL
0.5 mM 3.79 mL 18.96 mL 37.92 mL
1 mM 1.9 mL 9.48 mL 18.96 mL
5 mM 0.38 mL 1.9 mL 3.79 mL

*The above data is based on the productmolecular weight 527.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19071
Actions Inhibitor
CAS No. 2244451-48-5
Formula C23H24Cl2N2O6S
M. Wt 527.42
Solubility DMSO
Purity >98%
Synonyms BI 4916; BI4916
SMILES O=C(OCC)CS(=O)(C1=CC=C([[email protected]](NC(C(N2C)=CC3=C2C=C(C)C(Cl)=C3Cl)=O)CO)C=C1)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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