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BI 703704

Soluble Guanylate Cyclase Activator

BI 703704 is a potent soluble guanylate cyclase (sGC) activator that enhances intracellular signaling pathways through increased cGMP levels. It has demonstrated efficacy in inhibiting the progression of diabetic nephropathy in the ZSF1 rat model, making it a valuable tool for studying renal complications associated with diabetes. This compound is useful for research on cardiovascular and metabolic diseases, particularly those involving sGC modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	2740807-77-4
Applications	Soluble Guanylate Cyclase Activator
Formula	C₃₂H₃₇N₃O₄S
Molecular Weight	559.72
SMILES	CC1=CC(C2=CSC(N3C[C@H](CC4)[C@@H](C(O)=O)[C@H]4C3)=N2)=C(OCC5=CC=C(C(N6CCCCC6)=O)C=C5C)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.