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Biological Activity
BI-8626 is a specific inhibitor of the HUWE1 ubiquitin ligase with an IC50 of 0.9 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.7 mL | 113.49 mL | 226.98 mL |
| 0.5 mM | 4.54 mL | 22.7 mL | 45.4 mL |
| 1 mM | 2.27 mL | 11.35 mL | 22.7 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.54 mL |
*The above data is based on the productmolecular weight 440.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18787 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1875036-75-1 |
| Formula | C25H28N8 |
| M. Wt | 440.56 |
| Purity | >98% |
| Synonyms | BI8626; BI 8626; BI-8626 |
| SMILES | NCC1=CC(CNC2=C(N=CN=C3N4CCN(CC5=CC=CC=C5)CC4)C3=NC=N2)=CC=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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