BIBO3304 is a selective antagonist of the neuropeptide Y (NPY) Y1 receptor, exhibiting subnanomolar affinity with IC50 values of 0.38 nM for the human receptor and 0.72 nM for the rat receptor. This compound serves as a valuable tool for investigating the role of NPY signaling in various biological processes, including appetite regulation and anxiety-related behaviors. Its oral bioavailability makes it suitable for in vivo studies in pharmacological research and neurobiology.
BIBO3304 is a selective antagonist of the neuropeptide Y (NPY) Y1 receptor, exhibiting subnanomolar affinity with IC50 values of 0.38 nM for the human receptor and 0.72 nM for the rat receptor. This compound serves as a valuable tool for investigating the role of NPY signaling in various biological processes, including appetite regulation and anxiety-related behaviors. Its oral bioavailability makes it suitable for in vivo studies in pharmacological research and neurobiology.
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