BIBP3226 TFA

Catalog No.: A62187
NPY Y1/NPFF Receptor Antagonist
BIBP3226 TFA is a potent and selective antagonist of the neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptors. It exhibits inhibition constants (Kis) of 1.1 nM, 79 nM, and 108 nM for the rat NPY Y1, human NPFF2, and rat NPFF receptors, respectively. BIBP3226 TFA is utilized in research focused on anxiety and neuropeptide signaling pathways, providing valuable insights into the role of these receptors in various biological processes.
Grouped product items
Size Price Stock Qty
5mg
$125.00
In stock
10mg
$210.00
In stock
25mg
$460.00
In stock
50mg
$640.00
In stock
100mg
$880.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBIBP3226 TFA is a potent and selective antagonist of the neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptors. It exhibits inhibition constants (Kis) of 1.1 nM, 79 nM, and 108 nM for the rat NPY Y1, human NPFF2, and rat NPFF receptors, respectively. BIBP3226 TFA is utilized in research focused on anxiety and neuropeptide signaling pathways, providing valuable insights into the role of these receptors in various biological processes.
Product Information
Catalog NumA62187
FormulaC29H32F3N5O5
Molecular Weight587.59
CAS Number1068148-47-9
SMILESFC(C(O)=O)(F)F.OC(C=C1)=CC=C1CNC([C@@H](CCCNC(N)=N)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O
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