Biotin-nPEG-amine

Catalog No.: A82389
PROTAC Linkers
Biotin-nPEG-amine is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the efficient conjugation of target proteins with E3 ligases, enhancing the selective degradation of specific proteins within cellular environments. It is essential for researchers aiming to study protein degradation pathways and investigate therapeutic approaches in chemical biology.
Grouped product items
Size Price Stock Qty
25mg
$110.00
In stock
50mg
$165.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBiotin-nPEG-amine is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the efficient conjugation of target proteins with E3 ligases, enhancing the selective degradation of specific proteins within cellular environments. It is essential for researchers aiming to study protein degradation pathways and investigate therapeutic approaches in chemical biology.
Product Information
Catalog NumA82389
Formula(C2H4O)nC14H26N4O3S
Molecular Weight1299.61
CAS Number604786-74-5
SMILESNCCOCCOCCNC(CCCCC1C(NC(N2)=O)C2CS1)=O.[n]
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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