Fig. 1 · Structure
Documents & Downloads
Biotin-PEG2-C2-iodoacetamide
PROTAC Linkers
Biotin-PEG2-C2-iodoacetamide is a PEG-derived PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates targeted protein degradation by promoting the recruitment of E3 ligases to specific proteins of interest. It is particularly useful in studying protein regulation and function in various biological contexts, advancing research in targeted therapeutics and drug discovery.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 292843-75-5 |
| Applications | PROTAC Linkers |
| Formula | C18H31IN4O5S |
| Molecular Weight | 542.43 |
| SMILES | O=C(NCCOCCOCCNC(CI)=O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.