Biotin-PEG2-C6-azide is a PEG-based linker designed for the synthesis of PROTAC (Proteolysis Targeting Chimera) molecules. Featuring an azide functional group, it facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This reagent is instrumental in developing targeted protein degradation strategies and advancing research in cellular protein modulation and therapeutic discovery.
Biotin-PEG2-C6-azide is a PEG-based linker designed for the synthesis of PROTAC (Proteolysis Targeting Chimera) molecules. Featuring an azide functional group, it facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing partners, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This reagent is instrumental in developing targeted protein degradation strategies and advancing research in cellular protein modulation and therapeutic discovery.
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