Fig. 1 · Structure
Documents & Downloads
Biotin-PEG2-Mal
PROTAC Linker
Biotin-PEG2-Mal is a polyethylene glycol (PEG)-based PROTAC linker designed to facilitate molecular trafficking in targeted protein degradation applications. This compound serves as a versatile connector in the synthesis of PROTAC molecules, enhancing the stability and solubility of the resulting compounds. Its biotin functionality allows for efficient biotin-streptavidin labeling, aiding in the study of protein interactions and degradation pathways in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 305372-39-8 |
| Applications | PROTAC Linker |
| Formula | C23H35N5O7S |
| Molecular Weight | 525.62 |
| SMILES | O=C(NCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.