Fig. 1 · Structure
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Biotin-PEG2-NH-Boc
PROTAC Linker
Biotin-PEG2-NH-Boc is a PEG-based PROTAC linker that incorporates a biotin label for easy detection and affinity purification. This compound plays a crucial role in the design and synthesis of Proteolysis Targeting Chimeras (PROTACs), facilitating targeted protein degradation. Its unique structure allows for enhanced solubility and stability, making it suitable for a variety of biochemical assays and research applications aimed at modulating protein levels in cellular contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 175885-18-4 |
| Applications | PROTAC Linker |
| Formula | C21H38N4O6S |
| Molecular Weight | 474.61 |
| SMILES | O=C(OC(C)(C)C)NCCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.