Biotin-PEG4-Amide-C6-Azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with cyclooctyne derivatives such as DBCO or BCN. It is suitable for research applications in targeted protein degradation and the development of innovative therapeutic strategies.
Biotin-PEG4-Amide-C6-Azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with cyclooctyne derivatives such as DBCO or BCN. It is suitable for research applications in targeted protein degradation and the development of innovative therapeutic strategies.
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