Biotin-PEG4-amino-t-Bu-DADPS-C6-azide functions as a PEG-based PROTAC linker, facilitating the synthesis of targeted protein degraders. This compound is a versatile click chemistry reagent featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a valuable tool in chemical biology and drug discovery applications.
Biotin-PEG4-amino-t-Bu-DADPS-C6-azide functions as a PEG-based PROTAC linker, facilitating the synthesis of targeted protein degraders. This compound is a versatile click chemistry reagent featuring an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it supports strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a valuable tool in chemical biology and drug discovery applications.
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