Fig. 1 · Structure

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Biotin-PEG4-hydrazide

PROTAC Linkers

Biotin-PEG4-hydrazide is a biotinylated polyethylene glycol (PEG) linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of ligands to E3 ligase proteins, enhancing the targeted degradation of specific proteins within cells. Biotin-PEG4-hydrazide is suitable for various biological research applications, including the development of targeted protein degradation strategies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 756525-97-0
Applications PROTAC Linkers
Formula C21H39N5O7S
Molecular Weight 505.63
SMILES
O=C(NN)CCOCCOCCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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