Fig. 1 · Structure
Documents & Downloads
Biotin-PEG4-Picolyl azide
PROTAC Linkers
Biotin-PEG4-Picolyl azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds. Biotin-PEG4-Picolyl azide serves as an essential tool for advancing research in targeted protein degradation and other chemical biology applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2222687-71-8 |
| Applications | PROTAC Linkers |
| Formula | C27H42N8O7S |
| Molecular Weight | 622.74 |
| SMILES | O=C(NC1=CC=C(CN=[N+]=[N-])N=C1)CCOCCOCCOCCOCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.