Biotin-PEG4-Picolyl azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds. Biotin-PEG4-Picolyl azide serves as an essential tool for advancing research in targeted protein degradation and other chemical biology applications.
Biotin-PEG4-Picolyl azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide group that enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds. Biotin-PEG4-Picolyl azide serves as an essential tool for advancing research in targeted protein degradation and other chemical biology applications.
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