Fig. 1 · Structure

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Biotin-PEG4-SH

PROTAC Linkers

Biotin-PEG4-SH is a polyethylene glycol (PEG)-based linker designed for the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the conjugation of biotin to target proteins, enabling targeted degradation through the ubiquitin-proteasome pathway. Its primary applications include the development of novel PROTACs for targeted protein modulation in various biological studies and therapeutic investigations.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2762393-22-4
Applications PROTAC Linkers
Formula C20H37N3O6S2
Molecular Weight 479.65
SMILES
O=C(NCCOCCOCCOCCOCCS)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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