Biotin-PEG5-azide is a PEG-based PROTAC linker designed for targeted protein degradation applications. This compound features an azide moiety that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the conjugation of biomolecules containing alkyne, DBCO, or BCN groups. Its utility in synthesizing PROTACs makes it a valuable reagent for researchers investigating protein regulation and degradation pathways.
Biotin-PEG5-azide is a PEG-based PROTAC linker designed for targeted protein degradation applications. This compound features an azide moiety that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, facilitating the conjugation of biomolecules containing alkyne, DBCO, or BCN groups. Its utility in synthesizing PROTACs makes it a valuable reagent for researchers investigating protein regulation and degradation pathways.
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